Journal: Oncotarget

Article Title: A Gene Expression Profile Test for the Differential Diagnosis of Ovarian Versus Endometrial Cancers

doi:

Figure Lengend Snippet: Top 10 Biomarkers in the Tissue of Origin Endometrial Test Classification Algorithm

Article Snippet: The Pathwork Tissue of Origin Endometrial Test is the first microarray-based diagnostic test that has been successfully used to differentiate ovarian from endometrial cancers.

Techniques: Cell Function Assay, Wilms Tumor Assay

Journal: Oncotarget

Article Title: A Gene Expression Profile Test for the Differential Diagnosis of Ovarian Versus Endometrial Cancers

doi:

Figure Lengend Snippet: Accuracy of the Tissue of Origin Endometrial Test

Article Snippet: The Pathwork Tissue of Origin Endometrial Test is the first microarray-based diagnostic test that has been successfully used to differentiate ovarian from endometrial cancers.

Techniques: Biomarker Discovery

Journal: Oncotarget

Article Title: A Gene Expression Profile Test for the Differential Diagnosis of Ovarian Versus Endometrial Cancers

doi:

Figure Lengend Snippet: An ROC curve (A) for the Tissue of Origin Endometrial Test using results from the independent validation specimens gives an AUC value of 0.997. Distribution of similarity scores (B) obtained for the validation specimens shows clear separation of ovarian and endometrial cancer predictions.

Article Snippet: The Pathwork Tissue of Origin Endometrial Test is the first microarray-based diagnostic test that has been successfully used to differentiate ovarian from endometrial cancers.

Techniques: Biomarker Discovery

Journal: Oncotarget

Article Title: A Gene Expression Profile Test for the Differential Diagnosis of Ovarian Versus Endometrial Cancers

doi:

Figure Lengend Snippet: Tissue of Origin Endometrial Test Performance According to Specimen Attributes

Article Snippet: The Pathwork Tissue of Origin Endometrial Test is the first microarray-based diagnostic test that has been successfully used to differentiate ovarian from endometrial cancers.

Techniques:

Journal: Oncotarget

Article Title: A Gene Expression Profile Test for the Differential Diagnosis of Ovarian Versus Endometrial Cancers

doi:

Figure Lengend Snippet: Tissue of Origin Endometrial Test Performance According to Patient and Cancer Attributes

Article Snippet: The Pathwork Tissue of Origin Endometrial Test is the first microarray-based diagnostic test that has been successfully used to differentiate ovarian from endometrial cancers.

Techniques:

Journal: Oncotarget

Article Title: A Gene Expression Profile Test for the Differential Diagnosis of Ovarian Versus Endometrial Cancers

doi:

Figure Lengend Snippet: H&E stained sections (A, B, C and D) of an ovarian serous adenocarcinoma (A), an endometrial serous adenocarcinoma (B), a poorly differentiated ovarian adenocarcinoma (C) and a poorly differentiated endometrial adenocarcinoma (D) from the validation specimens show similar morphologic appearance of ovarian and endometrial serous adenocarcinomas (A and B) and ovarian and endometrial poorly differentiated adenocarcinomas (C and D). The Tissue of Origin Endometrial Test clearly distinguished between these tumors. The Tissue of Origin Endometrial Test result was ovarian with a similarity score of 96.4 for the ovarian serous adenocarcinoma (A), ovarian with a similarity score of 90.2 for the poorly differentiated ovarian adenocarcinoms (C), endometrial with a similarity score of 90.5 for the endometrial serous adenocarcinoma (B) and endometrial with a similarity score of 87.8 for the poorly differentiated endometrial adenocarcinoma (D). All images are at the same magnification. Bar = 50 μm.

Article Snippet: The Pathwork Tissue of Origin Endometrial Test is the first microarray-based diagnostic test that has been successfully used to differentiate ovarian from endometrial cancers.

Techniques: Staining, Biomarker Discovery

Journal: Oncotarget

Article Title: A Gene Expression Profile Test for the Differential Diagnosis of Ovarian Versus Endometrial Cancers

doi:

Figure Lengend Snippet: Reproducibility of the Tissue of Origin Endometrial Test

Article Snippet: The Pathwork Tissue of Origin Endometrial Test is the first microarray-based diagnostic test that has been successfully used to differentiate ovarian from endometrial cancers.

Techniques: Comparison

Journal: Oncotarget

Article Title: A Gene Expression Profile Test for the Differential Diagnosis of Ovarian Versus Endometrial Cancers

doi:

Figure Lengend Snippet: Morphologies on the Tissue of Origin Endometrial Test Panel

Article Snippet: The Pathwork Tissue of Origin Endometrial Test is the first microarray-based diagnostic test that has been successfully used to differentiate ovarian from endometrial cancers.

Techniques:

Journal: Oncotarget

Article Title: A Gene Expression Profile Test for the Differential Diagnosis of Ovarian Versus Endometrial Cancers

doi:

Figure Lengend Snippet: The report presents 2 similarity scores, one for ovarian and one for endometrial cancers. The two similarity scores add up to 100. The tissue type with the higher similarity score is the more likely tissue of origin. In the sample shown, ovarian cancer with a similarity score of 96.9 is the more likely tissue of origin.

Article Snippet: The Pathwork Tissue of Origin Endometrial Test is the first microarray-based diagnostic test that has been successfully used to differentiate ovarian from endometrial cancers.

Techniques:

Journal: Diagnostic Pathology

Article Title: A gene expression profile test to resolve head & neck squamous versus lung squamous cancers

doi: 10.1186/1746-1596-8-44

Figure Lengend Snippet: Top 20 biomarkers in the GEP-HN-LS test classification algorithm

Article Snippet: In order to better clarify HNSCC versus lung SCC, we have developed a gene expression based diagnostic test, GEP-HN-LS (Pathwork® Tissue of Origin Head & Neck Test, Pathwork Diagnostics, Inc., Redwood City, CA, USA), that can be used to aid in the differential diagnosis of squamous carcinomas of the head & neck and lung in FFPE tissue.

Techniques: Expressing, Binding Assay